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noldus phenotyper cages (Noldus Information Technology)

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Noldus Information Technology noldus phenotyper cages
Noldus Phenotyper Cages, supplied by Noldus Information Technology, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/noldus+phenotyper+cages/noldus+phenotyper/pmc12921699-110-27-27
Average 86 stars, based on 1 article reviews

noldus phenotyper cages - by Bioz Stars, 2026-10

86/100 stars

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Article Title: Proteomic Characterization of Striatal Neurabin Interactome and Its Sex Specific Impact on Motor Behavior.
Article Snippet: The striatum serves as the primary input nucleus of the basal ganglia.. Reversible protein phosphorylation in the post synaptic density (PSD) of medium spiny neurons (MSNs) modulates inputs from striatal afferents.. The context dependent regulation of PSD protein phosphorylation in direct-pathway medium spiny neurons (dMSNs) and indirect-pathway medium spiny neurons (iMSNs) works to differentially and synergistically impact striatal physiology and the execution of motor programs.

Article Title: Proteomic Characterization of Striatal Neurabin Interactome and Its Sex Specific Impact on Motor Behavior
Article Snippet: Mice were intraperitoneally injected daily for 5 days with saline (Teknova, S5812), or 3 mg/kg d-amphetamine (Sigma-aldrich, A5880) dissolved in saline at a volume of 10 mL/kg. .. Immediately following each intraperitoneal injection, open field locomotion was recorded in Noldus Phenotyper Cages (Noldus Information Technology, Wageningen, Netherlands). .. Distance traveled and center time were recorded and quantified using Noldus XT software.

Article Title: Proteomic Characterization of Striatal Neurabin Interactome and its Sex Specific Impact on Motor Behavior
Article Snippet: Mice were intraperitoneally (IP) injected daily for 5 days with saline (Teknova, S5812), or 3 mg/kg d-amphetamine (Sigma-aldrich, A5880) dissolved in saline at a volume of 10 ml/kg. .. Immediately following each intraperitoneal (i.p.) injection, open field locomotion was recorded in Noldus Phenotyper Cages (Noldus Information Technology, Wageningen, Netherlands). .. Distance traveled and center time were recorded and quantified using Noldus XT software.

Activity Assay:

Article Title: Neurobehavioral assessment of mice following repeated oral exposures to domoic acid during prenatal development.
Article Snippet: Domoic acid (DA) is an algal toxin which has been associated with significant neurotoxicity in humans, nonhuman primates, rodents, and marine mammals.. Developmental exposure to DA is believed to result in neurotoxicity that may persist into adulthood.. DA is produced by harmful algal blooms of Pseudo-nitzschia, raising concerns about the consumption of contaminated seafood.

other:

Article Title: A Novel Mouse Model of the Glucocorticoid Withdrawal Syndrome
Article Snippet: The Noldus Phenotyper cages were equipped with a freely accessible running wheel (diameter: 15 cm, width: 7 cm; PhenoWheel, Noldus Inc).

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A. The pain behaviors measured in the formalin spontaneous pain test were licking, biting, shaking and paw lifting. The test lasted 45 minutes after the injection of 15μL of formalin into the left hind paw (Mean ± SEM, two-way ANOVA with with Tukey’s multiple comparisons test, * p<0.05. ** p<0.01). B. Area under curve form behaviors were separated into two phases: Acute phase between 0-10min and inflammatory phase 10-45min (Mean ± SEM, Unpaired t-test, ** p<0.01). C-D. Post-formalin recovery was tested by placing the animals in a Phenotyper® observation cage 15min after the end of the formalin test, resting/prostration time and time spent rearing were measured (Mean ± SEM, two-way ANOVA with with Tukey’s multiple comparisons test, * p<0.05. ** p<0.01. and **** p<0.001).

Journal: bioRxiv

Article Title: Two pore domain THIK2 channel is involved in acute and chronic pain signal regulation

doi: 10.1101/2025.08.08.669258

Figure Lengend Snippet: A. The pain behaviors measured in the formalin spontaneous pain test were licking, biting, shaking and paw lifting. The test lasted 45 minutes after the injection of 15μL of formalin into the left hind paw (Mean ± SEM, two-way ANOVA with with Tukey’s multiple comparisons test, * p<0.05. ** p<0.01). B. Area under curve form behaviors were separated into two phases: Acute phase between 0-10min and inflammatory phase 10-45min (Mean ± SEM, Unpaired t-test, ** p<0.01). C-D. Post-formalin recovery was tested by placing the animals in a Phenotyper® observation cage 15min after the end of the formalin test, resting/prostration time and time spent rearing were measured (Mean ± SEM, two-way ANOVA with with Tukey’s multiple comparisons test, * p<0.05. ** p<0.01. and **** p<0.001).

Article Snippet: To assess this, animals previously subjected to the formalin test and, 15 minutes after its completion, were placed in a Noldus Phenotyper® observation cage.

Techniques: Injection

( A ) Diagram showing the dimensions (30 cm W × 30 cm D × 35 cm H) of a Noldus PhenoTyper 3000 and Noldus behavior recording and analysis software, EthoVision XT17. ( B ) Schematic for the IR-sensitive camera setup for top-view and front-view video recording. The top-view camera is centrally positioned on the ceiling to capture the horizontal activities. The front-view camera, mounted at a height of 9 cm above the floor level, points towards an imaginary threshold line that indicates the event of a mouse’s vertical stretching. ( C-E ) Diagrams presenting the height and dimensions of cage accessories (C) in stretch-promoting high cage and the cage setup from top view (D) and front view (E). ( F ) A representative image showing two mice stretching in a high cage. ( G-I ) Cartoon showing the height and dimensions of cage accessories (G) in control low cage and the cage setup from top view (H) and front view (I). ( J ) An example picture showing two animals moving between cage compartments through dividers holes in a low cage. ( K ) Top view of the dimension and setup of a sound-attenuating chamber (100 cm W × 70 cm D × 55 cm H) that encloses two PhenoTypers. ( L ) Schematic presentation of front view of two sound-attenuating chambers stacked on a rack and the computer system for top-view tracking and front-view tracking. ( M, N ) Pictures showing the behavior system setup in the lab (M) and the interior look of a sound-attenuating chamber (N).

Journal: bioRxiv

Article Title: A novel mouse model of voluntary stretching and its application in breast cancer research

doi: 10.1101/2025.01.24.634735

Figure Lengend Snippet: ( A ) Diagram showing the dimensions (30 cm W × 30 cm D × 35 cm H) of a Noldus PhenoTyper 3000 and Noldus behavior recording and analysis software, EthoVision XT17. ( B ) Schematic for the IR-sensitive camera setup for top-view and front-view video recording. The top-view camera is centrally positioned on the ceiling to capture the horizontal activities. The front-view camera, mounted at a height of 9 cm above the floor level, points towards an imaginary threshold line that indicates the event of a mouse’s vertical stretching. ( C-E ) Diagrams presenting the height and dimensions of cage accessories (C) in stretch-promoting high cage and the cage setup from top view (D) and front view (E). ( F ) A representative image showing two mice stretching in a high cage. ( G-I ) Cartoon showing the height and dimensions of cage accessories (G) in control low cage and the cage setup from top view (H) and front view (I). ( J ) An example picture showing two animals moving between cage compartments through dividers holes in a low cage. ( K ) Top view of the dimension and setup of a sound-attenuating chamber (100 cm W × 70 cm D × 55 cm H) that encloses two PhenoTypers. ( L ) Schematic presentation of front view of two sound-attenuating chambers stacked on a rack and the computer system for top-view tracking and front-view tracking. ( M, N ) Pictures showing the behavior system setup in the lab (M) and the interior look of a sound-attenuating chamber (N).

Article Snippet: Using food, water, and enrichment in the home cage as motivators for stretching, a two-week 24/7 behavior monitoring was conducted in a video-based customizable home-cage behavior tracking system, Noldus PhenoTyper, to promote self-stretching in FVB mice.

Techniques: Software, Control

Overview of the experimental setup. Mice started between 10 and 15 weeks of age and underwent testing via T‐maze, Morris water maze (MWM), PhenoTyper cages and a series of MRI scans. AN, anxiety; DL, discrimination learning; RL, reversal learning; SB, spontaneous behavior.

Journal: Genes, Brain, and Behavior

Article Title: Learning, memory and blood–brain barrier pathology in Duchenne muscular dystrophy mice lacking Dp427, or Dp427 and Dp140

doi: 10.1111/gbb.12895

Figure Lengend Snippet: Overview of the experimental setup. Mice started between 10 and 15 weeks of age and underwent testing via T‐maze, Morris water maze (MWM), PhenoTyper cages and a series of MRI scans. AN, anxiety; DL, discrimination learning; RL, reversal learning; SB, spontaneous behavior.

Article Snippet: A PhenoTyper automated home‐cage (Noldus PhenoTyper 3000, Noldus Information Technology), with transparent Perspex walls (30 × 30 × 35 cm) and opaque Perspex floor, was used to assess the mice's behavior.

Techniques:

Discrimination‐ and reversal learning with cognition wall and anxiety in PhenoTyper cages for WT ( n = 21), mdx ( n = 23–25) and mdx 4cv ( n = 22–23) mice. 80% success rate was calculated over a time window of 30 entries. (A) Survival curve of discrimination learning trials. Mdx and mdx 4cv mice were significantly faster in reaching the 80% criterium than WTs during discrimination learning. (B) Survival curves of reversal learning trials. No differences were found between groups. (C). Grey area (phase 2) represents the time the light was on. All groups showed a significant response to the light in phase 2 compared with baseline measurements of 24 h earlier. No differences were found between groups in the anxiety response. Asterisks indicate *** p < 0.001.

Journal: Genes, Brain, and Behavior

Article Title: Learning, memory and blood–brain barrier pathology in Duchenne muscular dystrophy mice lacking Dp427, or Dp427 and Dp140

doi: 10.1111/gbb.12895

Figure Lengend Snippet: Discrimination‐ and reversal learning with cognition wall and anxiety in PhenoTyper cages for WT ( n = 21), mdx ( n = 23–25) and mdx 4cv ( n = 22–23) mice. 80% success rate was calculated over a time window of 30 entries. (A) Survival curve of discrimination learning trials. Mdx and mdx 4cv mice were significantly faster in reaching the 80% criterium than WTs during discrimination learning. (B) Survival curves of reversal learning trials. No differences were found between groups. (C). Grey area (phase 2) represents the time the light was on. All groups showed a significant response to the light in phase 2 compared with baseline measurements of 24 h earlier. No differences were found between groups in the anxiety response. Asterisks indicate *** p < 0.001.

Techniques:

Spontaneous behavior in PhenoTyper cages for WT ( n = 21), mdx ( n = 23) and mdx 4cv ( n = 22) mice. (A) Average velocity was lower in mdx mice compared with WT mice during the dark phase. (B) The duration of active behavior was shorter in both DMD models compared with WTs in the dark phase. (C) Mdx and mdx 4cv mice showed a smaller change in activity in anticipation of the start of the dark phase, compared with WT mice. (D) Long movement threshold values revealed decreases in threshold for both mdx and mdx 4cv mice compared with WTs (E) Maximum velocity of long movement segment was decreased in mdx compared with WT mice. (F) Long movement arrest threshold was significantly lower in mdx mice compared with WTs. Asterisks indicate * p < 0.05, ** p < 0.01, *** p < 0.001. Cartoons are taken from Loos et al. 2014.

Journal: Genes, Brain, and Behavior

Article Title: Learning, memory and blood–brain barrier pathology in Duchenne muscular dystrophy mice lacking Dp427, or Dp427 and Dp140

doi: 10.1111/gbb.12895

Figure Lengend Snippet: Spontaneous behavior in PhenoTyper cages for WT ( n = 21), mdx ( n = 23) and mdx 4cv ( n = 22) mice. (A) Average velocity was lower in mdx mice compared with WT mice during the dark phase. (B) The duration of active behavior was shorter in both DMD models compared with WTs in the dark phase. (C) Mdx and mdx 4cv mice showed a smaller change in activity in anticipation of the start of the dark phase, compared with WT mice. (D) Long movement threshold values revealed decreases in threshold for both mdx and mdx 4cv mice compared with WTs (E) Maximum velocity of long movement segment was decreased in mdx compared with WT mice. (F) Long movement arrest threshold was significantly lower in mdx mice compared with WTs. Asterisks indicate * p < 0.05, ** p < 0.01, *** p < 0.001. Cartoons are taken from Loos et al. 2014.

Techniques: Activity Assay

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